Jun 14, - You can contract hepatitis C by coming into direct contact with an infected person's blood. It can also be transmitted by contact with bodily fluids including saliva or semen of an infected person, but this is rare. HCV may be more likely to spread through sexual contact if you: have multiple sexual partners.Oral sex · Other forms of transmission · Risk factors · Prevention. Mar 8, - Background: Hepatitis C virus (HCV) infection is an important cause of liver disease worldwide. Identification of risk factors can guide screening.